Constitutive activation of CREB in mice enhances temporal association learning and increases hippocampal CA1 neuronal spine density and complexity

Transcription factor CREB is believed to play essential roles in the formation of long-term memory (LTM), but not in learning and short-term memory (STM). Surprisingly, we previously showed that transgenic mice expressing a dominant active mutant of CREB (DIEDML) in the forebrain (DIEDML mice) demon...

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Detalles Bibliográficos
Autores principales: Serita, Tatsurou, Fukushima, Hotaka, Kida, Satoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5307365/
https://www.ncbi.nlm.nih.gov/pubmed/28195219
http://dx.doi.org/10.1038/srep42528

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5307365/
https://www.ncbi.nlm.nih.gov/pubmed/28195219
http://dx.doi.org/10.1038/srep42528

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