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Baseline autoantibodies preferentially impact abatacept efficacy in patients with rheumatoid arthritis who are biologic naïve: 6-month results from a real-world, international, prospective study

OBJECTIVES: To determine the impact of baseline rheumatoid factor (RF) and anticyclic citrullinated peptide (anti-CCP) status on the clinical efficacy of intravenous abatacept in biologic-naïve patients with rheumatoid arthritis (RA) enrolled in the real-world ACTION study. METHODS: Clinical outcome...

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Detalles Bibliográficos
Autores principales: Alten, Rieke, Nüßlein, Hubert G, Mariette, Xavier, Galeazzi, Mauro, Lorenz, Hanns-Martin, Cantagrel, Alain, Chartier, Melanie, Poncet, Coralie, Rauch, Christiane, Le Bars, Manuela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5307376/
https://www.ncbi.nlm.nih.gov/pubmed/28243468
http://dx.doi.org/10.1136/rmdopen-2016-000345