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Design, synthesis and biological potentials of novel tetrahydroimidazo[1,2-a]pyrimidine derivatives

BACKGROUND: A novel series of 5-(substituted aldehyde)-7-methyl-3-oxo-N-phenyl-2-((3,4,5,6-tetrahydroxytetrahydro-2H-pyran-2-yl)methylene)-1,2,3,5-tetrahydroimidazo[1,2-a]pyrimidine-6-carboxamide analogues (1–24) was synthesized using the Biginelli condensation. RESULTS AND DISCUSSION: The synthesiz...

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Detalles Bibliográficos
Autores principales: Rani, Jyoti, Saini, Monika, Kumar, Sanjiv, Verma, Prabhakar Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5307425/
https://www.ncbi.nlm.nih.gov/pubmed/28246545
http://dx.doi.org/10.1186/s13065-017-0245-9