Medulloblastoma and ependymoma cells display increased levels of 5-carboxylcytosine and elevated TET1 expression

BACKGROUND: Alteration of DNA methylation (5-methylcytosine, 5mC) patterns represents one of the causes of tumorigenesis and cancer progression. Tet proteins can oxidise 5mC to 5-hydroxymethylcytosine (5hmC), 5-formylcytosine and 5-carboxylcytosine (5caC). Although the roles of these oxidised forms...

Descripción completa

Detalles Bibliográficos
Autores principales: Ramsawhook, Ashley, Lewis, Lara, Coyle, Beth, Ruzov, Alexey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5307644/
https://www.ncbi.nlm.nih.gov/pubmed/28228863
http://dx.doi.org/10.1186/s13148-016-0306-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5307644/
https://www.ncbi.nlm.nih.gov/pubmed/28228863
http://dx.doi.org/10.1186/s13148-016-0306-2

Ejemplares similares