Cargando…
Medulloblastoma and ependymoma cells display increased levels of 5-carboxylcytosine and elevated TET1 expression
BACKGROUND: Alteration of DNA methylation (5-methylcytosine, 5mC) patterns represents one of the causes of tumorigenesis and cancer progression. Tet proteins can oxidise 5mC to 5-hydroxymethylcytosine (5hmC), 5-formylcytosine and 5-carboxylcytosine (5caC). Although the roles of these oxidised forms...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2017
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5307644/ https://www.ncbi.nlm.nih.gov/pubmed/28228863 http://dx.doi.org/10.1186/s13148-016-0306-2 |