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Tacrolimus in the prevention of adverse pregnancy outcomes and diabetes-associated embryopathies in obese and diabetic mice

BACKGROUND: T2DM is a high-risk pregnancy with adverse fetal and maternal outcomes including repeated miscarriages and fetal malformations. Despite the established association between placental insufficiency and poor maternal Th1-adaptability to the development of pregnancy complications in T2DM, th...

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Detalles Bibliográficos
Autores principales: Albaghdadi, Ahmad J. H., Hewitt, Melanie A., Putos, Samantha M., Wells, Michael, Ozolinš, Terence R. S., Kan, Frederick W. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5307666/
https://www.ncbi.nlm.nih.gov/pubmed/28193233
http://dx.doi.org/10.1186/s12967-017-1137-4