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Transient IKK2 activation in astrocytes initiates selective non-cell-autonomous neurodegeneration
BACKGROUND: Neuroinflammation is associated with a wide range of neurodegenerative disorders, however the specific contribution to individual disease pathogenesis and selective neuronal cell death is not well understood. Inflammatory cerebellar ataxias are neurodegenerative diseases occurring in var...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5307695/ https://www.ncbi.nlm.nih.gov/pubmed/28193238 http://dx.doi.org/10.1186/s13024-017-0157-0 |