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Transient IKK2 activation in astrocytes initiates selective non-cell-autonomous neurodegeneration

BACKGROUND: Neuroinflammation is associated with a wide range of neurodegenerative disorders, however the specific contribution to individual disease pathogenesis and selective neuronal cell death is not well understood. Inflammatory cerebellar ataxias are neurodegenerative diseases occurring in var...

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Detalles Bibliográficos
Autores principales:	Lattke, Michael, Reichel, Stephanie N., Magnutzki, Alexander, Abaei, Alireza, Rasche, Volker, Walther, Paul, Calado, Dinis P., Ferger, Boris, Wirth, Thomas, Baumann, Bernd
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5307695/ https://www.ncbi.nlm.nih.gov/pubmed/28193238 http://dx.doi.org/10.1186/s13024-017-0157-0

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