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Secretion of biologically active pancreatitis-associated protein I (PAP) by genetically modified dairy Lactococcus lactis NZ9000 in the prevention of intestinal mucositis

BACKGROUND: Mucositis is one of the most relevant gastrointestinal inflammatory conditions in humans, generated by the use of chemotherapy drugs, such as 5-fluoracil (5-FU). 5-FU-induced mucositis affects 80% of patients undergoing oncological treatment causing mucosal gut dysfunctions and great dis...

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Detalles Bibliográficos
Autores principales: Carvalho, Rodrigo D., Breyner, Natalia, Menezes-Garcia, Zelia, Rodrigues, Nubia M., Lemos, Luisa, Maioli, Tatiane U., da Gloria Souza, Danielle, Carmona, Denise, de Faria, Ana M. C., Langella, Philippe, Chatel, Jean-Marc, Bermúdez-Humarán, Luis G., Figueiredo, Henrique C. P., Azevedo, Vasco, de Azevedo, Marcela S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5307810/
https://www.ncbi.nlm.nih.gov/pubmed/28193209
http://dx.doi.org/10.1186/s12934-017-0624-x