Malondialdehyde-acetaldehyde (MAA) adducted surfactant protein induced lung inflammation is mediated through scavenger receptor a (SR-A1)

BACKGROUND: Co-exposure to cigarette smoke and alcohol leads to the generation of high concentrations of acetaldehyde and malondialdehyde in the lung. These aldehydes being highly electrophilic in nature react with biologically relevant proteins such as surfactant protein D (SPD) through a Schiff ba...

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Detalles Bibliográficos
Autores principales: Sapkota, Muna, DeVasure, Jane M., Kharbanda, Kusum K., Wyatt, Todd A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5307820/
https://www.ncbi.nlm.nih.gov/pubmed/28193223
http://dx.doi.org/10.1186/s12931-017-0517-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5307820/
https://www.ncbi.nlm.nih.gov/pubmed/28193223
http://dx.doi.org/10.1186/s12931-017-0517-x

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