Substitution of ethambutol with linezolid during the intensive phase of treatment of pulmonary tuberculosis: study protocol for a prospective, multicenter, randomized, open-label, phase II trial

BACKGROUND: Linezolid, an oxazolidinone, substantially improves treatment outcomes of multidrug-resistant tuberculosis and extensively drug-resistant tuberculosis. We started a trial to test whether the use of linezolid instead of ethambutol could increase the rate of sputum culture conversion as of...

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Detalles Bibliográficos
Autores principales: Lee, Ji Yeon, Kim, Deog Kyeom, Lee, Jung-Kyu, Yoon, Ho Il, Jeong, Ina, Heo, Eunyoung, Park, Young Sik, Lee, Jae Ho, Park, Sung Soo, Lee, Sang-Min, Lee, Chang-Hoon, Lee, Jinwoo, Choi, Sun Mi, Park, Jong Sun, Joh, Joon-Sung, Cho, Young-Jae, Lee, Yeon Joo, Kim, Se Joong, Hwang, Young Ran, Kim, Hyeonjeong, Ki, Jongeun, Choi, Hyungsook, Han, Jiyeon, Ahn, Heejung, Hahn, Seokyung, Yim, Jae-Joon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5307889/
https://www.ncbi.nlm.nih.gov/pubmed/28193240
http://dx.doi.org/10.1186/s13063-017-1811-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5307889/
https://www.ncbi.nlm.nih.gov/pubmed/28193240
http://dx.doi.org/10.1186/s13063-017-1811-0

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