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Screening of breast cancer stem cell inhibitors using a protein kinase inhibitor library

BACKGROUND: Cancer stem cells (CSCs), a subpopulation in tumors, are known to cause drug resistance, tumor recurrence and metastasis. Based on the characteristic formation of mammospheres in in vitro conditions, the mammosphere formation assay has become an essential tool for quantifying CSC activit...

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Detalles Bibliográficos
Autores principales: Choi, Hack Sun, Kim, Dal-Ah, Chung, Heesung, Park, In Ho, Kim, Bo Hye, Oh, Eok-Soo, Kang, Duk-Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5307923/
https://www.ncbi.nlm.nih.gov/pubmed/28289331
http://dx.doi.org/10.1186/s12935-017-0392-z