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Strategies to Extend Thrombolytic Time Window for Ischemic Stroke Treatment: An Unmet Clinical Need

To date, reperfusion with tissue plasminogen activator (tPA) remains the gold standard treatment for ischemic stroke. However, when tPA is given beyond 4.5 hours of stroke onset, deleterious effects of the drug ensue, especially, hemorrhagic transformation (HT), which causes the most significant mor...

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Detalles Bibliográficos
Autores principales: Peña, Ike dela, Borlongan, Cesar, Shen, Guofang, Davis, Willie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Stroke Society 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5307939/
https://www.ncbi.nlm.nih.gov/pubmed/28178410
http://dx.doi.org/10.5853/jos.2016.01515