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Targeted gene knock-in by CRISPR/Cas ribonucleoproteins in porcine zygotes

The domestic pig is an important “dual purpose” animal model for agricultural and biomedical applications. There is an emerging consensus in the biomedical community for the use of large animal models such as pigs to either serve as an alternative, or complement investigations from the mouse. Howeve...

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Detalles Bibliográficos
Autores principales: Park, Ki-Eun, Powell, Anne, Sandmaier, Shelley E. S., Kim, Chan-Mi, Mileham, Alan, Donovan, David M., Telugu, Bhanu P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5307959/
https://www.ncbi.nlm.nih.gov/pubmed/28195163
http://dx.doi.org/10.1038/srep42458