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Targeted gene knock-in by CRISPR/Cas ribonucleoproteins in porcine zygotes
The domestic pig is an important “dual purpose” animal model for agricultural and biomedical applications. There is an emerging consensus in the biomedical community for the use of large animal models such as pigs to either serve as an alternative, or complement investigations from the mouse. Howeve...
Autores principales: | Park, Ki-Eun, Powell, Anne, Sandmaier, Shelley E. S., Kim, Chan-Mi, Mileham, Alan, Donovan, David M., Telugu, Bhanu P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5307959/ https://www.ncbi.nlm.nih.gov/pubmed/28195163 http://dx.doi.org/10.1038/srep42458 |
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