How Native and Alien Metal Cations Bind ATP: Implications for Lithium as a Therapeutic Agent

Adenosine triphosphate (ATP), the major energy currency of the cell, exists in solution mostly as ATP-Mg. Recent experiments suggest that Mg(2+) interacts with the highly charged ATP triphosphate group and Li(+) can co-bind with the native Mg(2+) to form ATP-Mg-Li and modulate the neuronal purine re...

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Detalles Bibliográficos
Autores principales: Dudev, Todor, Grauffel, Cédric, Lim, Carmay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5307966/
https://www.ncbi.nlm.nih.gov/pubmed/28195155
http://dx.doi.org/10.1038/srep42377

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5307966/
https://www.ncbi.nlm.nih.gov/pubmed/28195155
http://dx.doi.org/10.1038/srep42377

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