Role of p38(alpha/beta) MAP Kinase in Cell Susceptibility to Clostridium sordellii Lethal Toxin and Clostridium difficile Toxin B

Lethal Toxin from Clostridium sordellii (TcsL), which is casually involved in the toxic shock syndrome and in gas gangrene, enters its target cells by receptor-mediated endocytosis. Inside the cell, TcsL mono-O-glucosylates and thereby inactivates Rac/Cdc42 and Ras subtype GTPases, resulting in acti...

Descripción completa

Detalles Bibliográficos
Autores principales: Schelle, Ilona, Bruening, Janina, Buetepage, Mareike, Genth, Harald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5308236/
https://www.ncbi.nlm.nih.gov/pubmed/28025502
http://dx.doi.org/10.3390/toxins9010002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5308236/
https://www.ncbi.nlm.nih.gov/pubmed/28025502
http://dx.doi.org/10.3390/toxins9010002

Ejemplares similares