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Role of p38(alpha/beta) MAP Kinase in Cell Susceptibility to Clostridium sordellii Lethal Toxin and Clostridium difficile Toxin B
Lethal Toxin from Clostridium sordellii (TcsL), which is casually involved in the toxic shock syndrome and in gas gangrene, enters its target cells by receptor-mediated endocytosis. Inside the cell, TcsL mono-O-glucosylates and thereby inactivates Rac/Cdc42 and Ras subtype GTPases, resulting in acti...
Autores principales: | Schelle, Ilona, Bruening, Janina, Buetepage, Mareike, Genth, Harald |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5308236/ https://www.ncbi.nlm.nih.gov/pubmed/28025502 http://dx.doi.org/10.3390/toxins9010002 |
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