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A Novel Toxin from Haplopelma lividum Selectively Inhibits the Na(V)1.8 Channel and Possesses Potent Analgesic Efficacy

Spider venoms are a complex mixture of peptides with a large number of neurotoxins targeting ion channels. Although thousands of peptide toxins have been identified from venoms of numerous species of spiders, many unknown species urgently need to be investigated. In this study, a novel sodium channe...

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Detalles Bibliográficos
Autores principales: Meng, Ping, Huang, Honggang, Wang, Gan, Yang, Shilong, Lu, Qiuming, Liu, Jingze, Lai, Ren, Rong, Mingqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5308240/
https://www.ncbi.nlm.nih.gov/pubmed/28035974
http://dx.doi.org/10.3390/toxins9010007