miR182 activates the Ras–MEK–ERK pathway in human oral cavity squamous cell carcinoma by suppressing RASA1 and SPRED1

PURPOSE: The constitutive activation of the Ras–MEK–ERK signaling pathway in oral cavity squamous cell carcinoma (OSCC) has been found to be tightly controlled at multiple levels under physiological conditions. RASA1 and SPRED1 are two important negative regulators of this pathway, but the exact reg...

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Detalles Bibliográficos
Autores principales: Wang, Jinhui, Wang, Wei, Li, Jichen, Wu, Liji, Song, Mei, Meng, Qinggang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5308578/
https://www.ncbi.nlm.nih.gov/pubmed/28223824
http://dx.doi.org/10.2147/OTT.S121864

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5308578/
https://www.ncbi.nlm.nih.gov/pubmed/28223824
http://dx.doi.org/10.2147/OTT.S121864

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