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CUL4A promotes proliferation and metastasis of colorectal cancer cells by regulating H3K4 trimethylation in epithelial–mesenchymal transition

Increasing evidence suggests that CUL4A, a ubiquitin ligase, is involved in the promotion of cancer malignancy and correlated with worse clinical prognosis in several kinds of human cancers. Although its effect and mechanism on the progression of colorectal cancer (CRC) remain unknown. Our clinical...

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Detalles Bibliográficos
Autores principales: Sui, Xuemei, Zhou, Hong, Zhu, Lei, Wang, Deqiang, Fan, Sumei, Zhao, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5308582/
https://www.ncbi.nlm.nih.gov/pubmed/28223829
http://dx.doi.org/10.2147/OTT.S118897