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Llgl1 prevents metaplastic survival driven by epidermal growth factor dependent migration

We have previously demonstrated that Llgl1 loss results in a gain of mesenchymal phenotypes and a loss of apicobasal and planar polarity. We now demonstrate that these changes represent a fundamental shift in cellular phenotype. Llgl1 regulates the expression of multiple cell identity markers, inclu...

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Detalles Bibliográficos
Autores principales: Greenwood, Erin, Maisel, Sabrina, Ebertz, David, Russ, Atlantis, Pandey, Ritu, Schroeder, Joyce
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5308616/
https://www.ncbi.nlm.nih.gov/pubmed/27542214
http://dx.doi.org/10.18632/oncotarget.11320