Deficient for endoplasmic reticulum calcium sensors Stim1 and Stim2 affects aberrant antibody affinity maturation in B cells

Antigen specific B cells undergo a process termed affinity maturation in the germinal centers of secondary lymphoid organs where B cells with high affinity receptors are selected to mature into antibody-producing cells or to the memory B cell pool. It is known that B cell antigen receptor (BCR) sign...

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Detalles Bibliográficos
Autores principales: Mao, Xuhua, Zhang, Jianfeng, Han, Yue, Luan, Chao, Hu, Yu, Hao, Zhimin, Chen, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper: Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5308623/
https://www.ncbi.nlm.nih.gov/pubmed/27572320
http://dx.doi.org/10.18632/oncotarget.11659

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5308623/
https://www.ncbi.nlm.nih.gov/pubmed/27572320
http://dx.doi.org/10.18632/oncotarget.11659

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