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Role of Jnk1 in development of neural precursors revealed by iPSC modeling

Jnk1-deficient mice manifest disrupted anterior commissure formation and loss of axonal and dendritic microtubule integrity. However, the mechanisms and the specific stages underlying the developmental defects remain to be elucidated. Here, we report the generation of Jnk1-deficient (Jnk1 KO) iPSCs...

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Detalles Bibliográficos
Autores principales: Zhang, Qian, Mao, Jian, Zhang, Xiaoxi, Fu, Haifeng, Xia, Siyuan, Yin, Zhinan, Liu, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5308626/
https://www.ncbi.nlm.nih.gov/pubmed/27556303
http://dx.doi.org/10.18632/oncotarget.11377