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Role of mir-15a/16-1 in early B cell development in a mouse model of chronic lymphocytic leukemia
In both human chronic lymphocytic leukemia (CLL) and the New Zealand Black (NZB) murine model of CLL, decreased levels of microRNAs miR-15a/16 play an important role in the disease. Here we investigate the effects of this microRNA on early steps of B cell development and the capacity of miR-15a-defi...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5308631/ https://www.ncbi.nlm.nih.gov/pubmed/27533467 http://dx.doi.org/10.18632/oncotarget.11290 |