Cargando…

Role of mir-15a/16-1 in early B cell development in a mouse model of chronic lymphocytic leukemia

In both human chronic lymphocytic leukemia (CLL) and the New Zealand Black (NZB) murine model of CLL, decreased levels of microRNAs miR-15a/16 play an important role in the disease. Here we investigate the effects of this microRNA on early steps of B cell development and the capacity of miR-15a-defi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Underbayev, Chingiz, Kasar, Siddha, Ruezinsky, William, Degheidy, Heba, Schneider, Joel Solomon, Marti, Gerald, Bauer, Steven R., Fraidenraich, Diego, Lightfoote, Marilyn M., Parashar, Vijay, Raveche, Elizabeth, Batish, Mona
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5308631/ https://www.ncbi.nlm.nih.gov/pubmed/27533467 http://dx.doi.org/10.18632/oncotarget.11290

Ejemplares similares

Alterations in the mir-15a/16-1 Loci Impairs Its Processing and Augments B-1 Expansion in De Novo Mouse Model of Chronic Lymphocytic Leukemia (CLL)
por: Kasar, Siddha, et al.
Publicado: (2016)

MicroRNAs and Induced Pluripotent Stem Cells for Human Disease Mouse Modeling
por: Underbayev, Chingiz, et al.
Publicado: (2012)

Therapeutic Implications of Activation of the Host Gene (Dleu2) Promoter for miR-15a/16-1 in Chronic Lymphocytic Leukemia (CLL)
por: Kasar, S, et al.
Publicado: (2013)

MicroRNAs in Acute Myeloid Leukemia and Other Blood Disorders
por: Yuan, Yao, et al.
Publicado: (2012)

Systemic in vivo lentiviral delivery of miR-15a/16 reduces malignancy in the NZB de novo mouse model of Chronic Lymphocytic Leukemia
por: Salerno, Erica, et al.
Publicado: (2011)

Fusion FISH Imaging: Single-Molecule Detection of Gene Fusion Transcripts In Situ
por: Markey, Fatu Badiane, et al.
Publicado: (2014)

Structural basis of KdpD histidine kinase binding to the second messenger c-di-AMP
por: Dutta, Anirudha, et al.
Publicado: (2021)

The Landscape of Regulatory Noncoding RNAs in Ewing’s Sarcoma
por: Barrett, Connor, et al.
Publicado: (2021)

Identification of a New Transcriptional Co-Regulator of STEAP1 in Ewing’s Sarcoma
por: Markey, Fatu Badiane, et al.
Publicado: (2021)

Structural basis of cyclic oligoadenylate binding to the transcription factor Csa3 outlines cross talk between type III and type I CRISPR systems
por: Xia, Pengjun, et al.
Publicado: (2022)

CircFISH: A Novel Method for the Simultaneous Imaging of Linear and Circular RNAs
por: Koppula, Aakash, et al.
Publicado: (2022)

IKAP—Identifying K mAjor cell Population groups in single-cell RNA-sequencing analysis
por: Chen, Yun-Ching, et al.
Publicado: (2019)

Humoral and Cellular Immunogenicity of COVID-19 Vaccinations in Patients with CLL
por: Sun, Clare, et al.
Publicado: (2021)

Mutational landscape and underlying mutational processes in chronic lymphocytic leukemia
por: Kasar, S., et al.
Publicado: (2016)

The evolutionary landscape of chronic lymphocytic leukemia treated with ibrutinib targeted therapy
por: Landau, Dan A., et al.
Publicado: (2017)

Rare Germline Variants in ATM Are Associated with Chronic Lymphocytic Leukemia
por: Tiao, Grace, et al.
Publicado: (2017)

Post-Transformation IGHV-IGHD-IGHJ Mutations in Chronic Lymphocytic Leukemia B Cells: Implications for Mutational Mechanisms and Impact on Clinical Course
por: Bagnara, Davide, et al.
Publicado: (2021)

Computer Simulation of Metastable Fluid States in the Lennard-Jones System
por: Raveché, Harold J., et al.
Publicado: (1976)

Antigenic presentation of heterologous epitopes engineered into the outer surface-exposed helix 4 loop region of human papillomavirus L1 capsomeres
por: Murata, Yoshihiko, et al.
Publicado: (2009)

Xenobiotics enhance laccase activity in alkali-tolerant γ-proteobacterium JB
por: Singh, Gursharan, et al.
Publicado: (2009)

Glove Vacuum-Assisted Wound Closure for the Scrotum
por: Siddha, Loka Vijayan, et al.
Publicado: (2014)

Role of the Surgical Glove in Modified Vacuum-Assisted Wound Healing
por: Hemmanur, Shankar Ram, et al.
Publicado: (2013)

Establishing CD19 B-cell reference control materials for comparable and quantitative cytometric expression analysis
por: Wang, Lili, et al.
Publicado: (2021)

Glutathione S transferase theta1 and mu1 gene polymorphisms and phenotypic expression of asthma in Egyptian children: a case–control study
por: El Rifai, Nihal, et al.
Publicado: (2014)

Prevalence, incidence and molecular characterization of tape worms in Al Taif governorate, KSA and the effectiveness of Spirulina platensis as a biological control in vitro
por: Al-Otaibi, Bedor O., et al.
Publicado: (2021)

Investigating the Targets of MIR-15a and MIR-16-1 in Patients with Chronic Lymphocytic Leukemia (CLL)
por: Hanlon, Katy, et al.
Publicado: (2009)

An Emerging Role for Epigenetics in Cerebral Palsy
por: Romero, Brigette, et al.
Publicado: (2021)

Novel circular RNAs of the apoptosis‐related BAX and BCL2L12 genes identified in a chronic lymphocytic leukemia cell line using nanopore sequencing
por: Kontos, Christos K., et al.
Publicado: (2023)

Whole Genome 5′-Methylcytosine Level Quantification in Cirrhotic HCV-Infected Egyptian Patients with and without Hepatocellular Carcinoma
por: Awad, Ahmed M., et al.
Publicado: (2020)

Hypertensive Urgency Secondary to a Malignant Pheochromocytoma and Its Complex Treatment Course: A Case Report
por: Elkammash, Amr, et al.
Publicado: (2022)

Allele-specific loss and transcription of the miR-15a/16-1 cluster in chronic lymphocytic leukemia
por: Veronese, A, et al.
Publicado: (2015)

Fault diagnosis and reconfiguration in flight control systems
por: Hajiyev, Chingiz, et al.
Publicado: (2003)

Voicebot and Chatbot design: flexible conversational interfaces with Amazon Alexa, Google Home, and Facebook Messenger
por: Batish, Rachel
Publicado: (2018)

A Japanese case of chronic lymphocytic leukemia with t (1;6)
por: Harada, Kayo, et al.
Publicado: (2012)

Cytoplasmic crystal inclusions in lymphocytes of chronic lymphocytic leukemia
por: Villuendas Vázquez, Òscar, et al.
Publicado: (2020)

Properties of Titanium Zirconium Molybdenum Alloy after Exposure to Indium at Elevated Temperatures
por: Metzger, Florian, et al.
Publicado: (2022)

In Silico and In Vitro Analyses to Repurpose Quercetin as a Human Pancreatic α-Amylase Inhibitor
por: Raut, Bimal K., et al.
Publicado: (2023)

Bit Error Rate Closed-Form Expressions for LoRa Systems under Nakagami and Rice Fading Channels
por: Ferreira Dias, Claudio, et al.
Publicado: (2019)

Thiopurine S-Methyltransferase as a Pharmacogenetic Biomarker: Significance of Testing and Review of Major Methods
por: Asadov, Chingiz, et al.
Publicado: (2017)

Influenza pandemic planning: One organization's experience
por: Amirov, Chingiz, et al.
Publicado: (2007)

Cannot write session to /tmp/vufind_sessions/sess_l56sgjgcmg7rs9en40gflc32p6