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Genome-wide gain-of-function screen for genes that induce epithelial-to-mesenchymal transition in breast cancer
Epithelial to mesenchymal transition (EMT) is a developmental program that has been implicated in progression, metastasis and therapeutic resistance of some carcinomas. To identify genes whose overexpression drives EMT, we screened a lentiviral expression library of 17000 human open reading frames (...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5308632/ https://www.ncbi.nlm.nih.gov/pubmed/27876705 http://dx.doi.org/10.18632/oncotarget.11314 |