Cargando…

Interleukin-6 increases matrix metalloproteinase-14 (MMP-14) levels via down-regulation of p53 to drive cancer progression

Matrix metalloproteinases (MMPs) play critical roles in cancer invasion and metastasis by digesting basement membrane and extracellular matrix (ECM). Much attention has focused on the enzymatic activities of MMPs; however, the regulatory mechanism of MMP expression remains elusive. By employing bioi...

Descripción completa

Detalles Bibliográficos
Autores principales: Cathcart, Jillian M., Banach, Anna, Liu, Alice, Chen, Jun, Goligorsky, Michael, Cao, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5308639/
https://www.ncbi.nlm.nih.gov/pubmed/27531896
http://dx.doi.org/10.18632/oncotarget.11243