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Interleukin-6 increases matrix metalloproteinase-14 (MMP-14) levels via down-regulation of p53 to drive cancer progression
Matrix metalloproteinases (MMPs) play critical roles in cancer invasion and metastasis by digesting basement membrane and extracellular matrix (ECM). Much attention has focused on the enzymatic activities of MMPs; however, the regulatory mechanism of MMP expression remains elusive. By employing bioi...
Autores principales: | Cathcart, Jillian M., Banach, Anna, Liu, Alice, Chen, Jun, Goligorsky, Michael, Cao, Jian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5308639/ https://www.ncbi.nlm.nih.gov/pubmed/27531896 http://dx.doi.org/10.18632/oncotarget.11243 |
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