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Lysosomal acid lipase in mesenchymal stem cell stimulation of tumor growth and metastasis
Bone marrow mesenchymal stem cells (MSCs) are an important participant in the tumor microenvironment, in which they promote tumor growth and progression. Here we report for the first time that depletion of lysosomal acid lipase (LAL) in MSCs impairs their abilities to stimulate tumor growth and meta...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5308640/ https://www.ncbi.nlm.nih.gov/pubmed/27531897 http://dx.doi.org/10.18632/oncotarget.11244 |