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Lysosomal acid lipase in mesenchymal stem cell stimulation of tumor growth and metastasis

Bone marrow mesenchymal stem cells (MSCs) are an important participant in the tumor microenvironment, in which they promote tumor growth and progression. Here we report for the first time that depletion of lysosomal acid lipase (LAL) in MSCs impairs their abilities to stimulate tumor growth and meta...

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Detalles Bibliográficos
Autores principales: Zhao, Ting, Yan, Cong, Du, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5308640/
https://www.ncbi.nlm.nih.gov/pubmed/27531897
http://dx.doi.org/10.18632/oncotarget.11244