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Deregulated FADD expression and phosphorylation in T-cell lymphoblastic lymphoma

In the present work, we show that T-cell lymphoblastic lymphoma cells exhibit a reduction of FADD availability in the cytoplasm, which may contribute to impaired apoptosis. In addition, we observe a reduction of FADD phosphorylation that inversely correlates with the proliferation capacity and tumor...

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Detalles Bibliográficos
Autores principales: Marín-Rubio, José L., de Arriba, María C., Cobos-Fernández, María A., González-Sánchez, Laura, Ors, Inmaculada, Sastre, Isabel, Fernández-Piqueras, José, Villa-Morales, María
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5308666/
https://www.ncbi.nlm.nih.gov/pubmed/27556297
http://dx.doi.org/10.18632/oncotarget.11370