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The role of nerve microenvironment for neurofibroma development

Deregulation of RAS signaling in Neurofibromatosis type 1 (NF1) results in the development of multiple neurofibromas, complex tumor of the peripheral nerves with no effective medical treatment. There is increasing evidences that neurofibroma initiates through loss of NF1 function in the Schwann cell...

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Detalles Bibliográficos
Autores principales: Liao, Chung-Ping, Pradhan, Sanjay, Chen, Zhiguo, Patel, Amish J., Booker, Reid C., Le, Lu Q.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5308667/
https://www.ncbi.nlm.nih.gov/pubmed/27517146
http://dx.doi.org/10.18632/oncotarget.11133