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RhoGDIα suppresses self-renewal and tumorigenesis of glioma stem cells

Glioma stem cells (GSCs) are a subset of tumor cells that drive glioma initiation and progression. The molecular mechanisms underlying the maintenance of GSCs are still poorly understood. Here we investigated the role of Rho GDP dissociation inhibitor α (RhoGDIα) in GSCs. RhoGDIα was down-regulated...

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Detalles Bibliográficos
Autores principales: Wu, Fan, Hu, Peishan, Li, Dengke, Hu, Yan, Qi, Yingjiao, Yin, Bin, Jiang, Tao, Yuan, Jiangang, Han, Wei, Peng, Xiaozhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5308677/
https://www.ncbi.nlm.nih.gov/pubmed/27557508
http://dx.doi.org/10.18632/oncotarget.11423