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Ligand dependent restoration of human TLR3 signaling and death in p53 mutant cells

Diversity within the p53 transcriptional network can arise from a matrix of changes that include target response element sequences and p53 expression level variations. We previously found that wild type p53 (WT p53) can regulate expression of most innate immune-related Toll-like-receptor genes (TLRs...

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Detalles Bibliográficos
Autores principales: Menendez, Daniel, Lowe, Julie M., Snipe, Joyce, Resnick, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5308678/
https://www.ncbi.nlm.nih.gov/pubmed/27533082
http://dx.doi.org/10.18632/oncotarget.11210