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A bivalent promoter contributes to stress-induced plasticity of CXCR4 in Ewing sarcoma
Tumor heterogeneity is a major impediment to cancer cures. Tumor cell heterogeneity can arise by irreversible genetic mutation, as well as by non-mutational mechanisms, which can be reversibly modulated by the tumor microenvironment and the epigenome. We recently reported that the chemokine receptor...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5308690/ https://www.ncbi.nlm.nih.gov/pubmed/27528222 http://dx.doi.org/10.18632/oncotarget.11240 |