A bivalent promoter contributes to stress-induced plasticity of CXCR4 in Ewing sarcoma

Tumor heterogeneity is a major impediment to cancer cures. Tumor cell heterogeneity can arise by irreversible genetic mutation, as well as by non-mutational mechanisms, which can be reversibly modulated by the tumor microenvironment and the epigenome. We recently reported that the chemokine receptor...

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Detalles Bibliográficos
Autores principales: Krook, Melanie A., Hawkins, Allegra G., Patel, Rajiv M., Lucas, David R., Van Noord, Raelene, Chugh, Rashmi, Lawlor, Elizabeth R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5308690/
https://www.ncbi.nlm.nih.gov/pubmed/27528222
http://dx.doi.org/10.18632/oncotarget.11240

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