Low-dose Actinomycin-D treatment re-establishes the tumoursuppressive function of P53 in RELA-positive ependymoma

Ependymomas in children can arise throughout all compartments of the central nervous system (CNS). Highly malignant paediatric ependymoma subtypes are Group A tumours of the posterior fossa (PF-EPN-A) and RELA-fusion positive (ST-EPN-RELA) tumours in the supratentorial compartment. It was repeatedly...

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Detalles Bibliográficos
Autores principales: Tzaridis, Theophilos, Milde, Till, Pajtler, Kristian W., Bender, Sebastian, Jones, David T. W., Müller, Simone, Wittmann, Andrea, Schlotter, Magdalena, Kulozik, Andreas E., Lichter, Peter, Collins, V. Peter, Witt, Olaf, Kool, Marcel, Korshunov, Andrey, Pfister, Stefan M., Witt, Hendrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5308696/
https://www.ncbi.nlm.nih.gov/pubmed/27556362
http://dx.doi.org/10.18632/oncotarget.11452

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5308696/
https://www.ncbi.nlm.nih.gov/pubmed/27556362
http://dx.doi.org/10.18632/oncotarget.11452

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