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Lactoferrin selectively triggers apoptosis in highly metastatic breast cancer cells through inhibition of plasmalemmal V-H+-ATPase

Breast cancer is the most common type of cancer affecting women. Despite the good prognosis when detected early, significant challenges remain in the treatment of metastatic breast cancer. The recruitment of the vacuolar H(+)-ATPase (V-H(+)-ATPase) to the plasma membrane, where it mediates the acidi...

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Detalles Bibliográficos
Autores principales: Pereira, Cátia S., Guedes, Joana P., Gonçalves, Marília, Loureiro, Luís, Castro, Lisandra, Gerós, Hernâni, Rodrigues, Lígia R., Côrte-Real, Manuela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5308717/
https://www.ncbi.nlm.nih.gov/pubmed/27556694
http://dx.doi.org/10.18632/oncotarget.11394