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Lactoferrin selectively triggers apoptosis in highly metastatic breast cancer cells through inhibition of plasmalemmal V-H+-ATPase
Breast cancer is the most common type of cancer affecting women. Despite the good prognosis when detected early, significant challenges remain in the treatment of metastatic breast cancer. The recruitment of the vacuolar H(+)-ATPase (V-H(+)-ATPase) to the plasma membrane, where it mediates the acidi...
Autores principales: | Pereira, Cátia S., Guedes, Joana P., Gonçalves, Marília, Loureiro, Luís, Castro, Lisandra, Gerós, Hernâni, Rodrigues, Lígia R., Côrte-Real, Manuela |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5308717/ https://www.ncbi.nlm.nih.gov/pubmed/27556694 http://dx.doi.org/10.18632/oncotarget.11394 |
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