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Knockdown of NEAT1 restrained the malignant progression of glioma stem cells by activating microRNA let-7e

Nuclear paraspeckle assembly transcript 1 (NEAT1), a long non-coding RNA, promotes oncogenesis in various tumors, including human gliomas. Herein, we studied the expression and function of NEAT1 in glioma stem cells (GSCs). Quantitative real-time PCR demonstrated that NEAT1 was upregulated in GSCs....

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Detalles Bibliográficos
Autores principales: Gong, Wei, Zheng, Jian, Liu, Xiaobai, Ma, Jun, Liu, Yunhui, Xue, Yixue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5308721/
https://www.ncbi.nlm.nih.gov/pubmed/27556696
http://dx.doi.org/10.18632/oncotarget.11403