Dual targeting of androgen receptor and mTORC1 by salinomycin in prostate cancer

Androgen receptor (AR) and PI3K/AKT/mTORC1 are major survival signals that drive prostate cancer to a lethal disease. Reciprocal activation of these oncogenic pathways from negative cross talks contributes to low/limited success of pathway-selective inhibitors in curbing prostate cancer progression....

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Detalles Bibliográficos
Autores principales: Mirkheshti, Nooshin, Park, Sulgi, Jiang, Shoulei, Cropper, Jodie, Werner, Sherry L., Song, Chung S., Chatterjee, Bandana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5308723/
https://www.ncbi.nlm.nih.gov/pubmed/27557496
http://dx.doi.org/10.18632/oncotarget.11404

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5308723/
https://www.ncbi.nlm.nih.gov/pubmed/27557496
http://dx.doi.org/10.18632/oncotarget.11404

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