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Recruitment of Fkh1 to replication origins requires precisely positioned Fkh1/2 binding sites and concurrent assembly of the pre-replicative complex

In budding yeast, activation of many DNA replication origins is regulated by their chromatin environment, whereas others fire in early S phase regardless of their chromosomal location. Several location-independent origins contain at least two divergently oriented binding sites for Forkhead (Fkh) tra...

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Detalles Bibliográficos
Autores principales: Reinapae, Allan, Jalakas, Kristiina, Avvakumov, Nikita, Lõoke, Marko, Kristjuhan, Kersti, Kristjuhan, Arnold
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5308776/
https://www.ncbi.nlm.nih.gov/pubmed/28141805
http://dx.doi.org/10.1371/journal.pgen.1006588