Cargando…
Cyp1b1 Regulates Ocular Fissure Closure Through a Retinoic Acid–Independent Pathway
PURPOSE: Mutations in the CYP1B1 gene are the most commonly identified genetic causes of primary infantile-onset glaucoma. Despite this disease association, the role of CYP1B1 in eye development and its in vivo substrate remain unknown. In the present study, we used zebrafish to elucidate the mechan...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Association for Research in Vision and Ophthalmology
2017
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5308778/ https://www.ncbi.nlm.nih.gov/pubmed/28192799 http://dx.doi.org/10.1167/iovs.16-20235 |