Chemotherapy induces adaptive drug resistance and metastatic potentials via phenotypic CXCR4-expressing cell state transition in ovarian cancer

Ovarian cancer (OVC) patients who receive chemotherapy often acquire drug resistance within one year. This can lead to tumor reoccurrence and metastasis, the major causes of mortality. We report a transient increase of a small distinctive CXCR4(High)/CD24(Low) cancer stem cell population (CXCR4(High...

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Detalles Bibliográficos
Autores principales: Lee, Hyun Hee, Bellat, Vanessa, Law, Benedict
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5308810/
https://www.ncbi.nlm.nih.gov/pubmed/28196146
http://dx.doi.org/10.1371/journal.pone.0171044

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5308810/
https://www.ncbi.nlm.nih.gov/pubmed/28196146
http://dx.doi.org/10.1371/journal.pone.0171044

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