A positive-strand RNA virus uses alternative protein-protein interactions within a viral protease/cofactor complex to switch between RNA replication and virion morphogenesis

The viruses of the family Flaviviridae possess a positive-strand RNA genome and express a single polyprotein which is processed into functional proteins. Initially, the nonstructural (NS) proteins, which are not part of the virions, form complexes capable of genome replication. Later on, the NS prot...

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Detalles Bibliográficos
Autores principales: Dubrau, Danilo, Tortorici, M. Alejandra, Rey, Félix A., Tautz, Norbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5308820/
https://www.ncbi.nlm.nih.gov/pubmed/28151973
http://dx.doi.org/10.1371/journal.ppat.1006134

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5308820/
https://www.ncbi.nlm.nih.gov/pubmed/28151973
http://dx.doi.org/10.1371/journal.ppat.1006134

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