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The scoring bias in reverse docking and the score normalization strategy to improve success rate of target fishing
Target fishing often relies on the use of reverse docking to identify potential target proteins of ligands from protein database. The limitation of reverse docking is the accuracy of current scoring funtions used to distinguish true target from non-target proteins. Many contemporary scoring function...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5308821/ https://www.ncbi.nlm.nih.gov/pubmed/28196116 http://dx.doi.org/10.1371/journal.pone.0171433 |