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Iterative sure independence screening EM-Bayesian LASSO algorithm for multi-locus genome-wide association studies

Genome-wide association study (GWAS) entails examining a large number of single nucleotide polymorphisms (SNPs) in a limited sample with hundreds of individuals, implying a variable selection problem in the high dimensional dataset. Although many single-locus GWAS approaches under polygenic backgrou...

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Detalles Bibliográficos
Autores principales: Tamba, Cox Lwaka, Ni, Yuan-Li, Zhang, Yuan-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5308866/
https://www.ncbi.nlm.nih.gov/pubmed/28141824
http://dx.doi.org/10.1371/journal.pcbi.1005357