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Iterative sure independence screening EM-Bayesian LASSO algorithm for multi-locus genome-wide association studies
Genome-wide association study (GWAS) entails examining a large number of single nucleotide polymorphisms (SNPs) in a limited sample with hundreds of individuals, implying a variable selection problem in the high dimensional dataset. Although many single-locus GWAS approaches under polygenic backgrou...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5308866/ https://www.ncbi.nlm.nih.gov/pubmed/28141824 http://dx.doi.org/10.1371/journal.pcbi.1005357 |