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Alterations in estrogen signalling pathways upon acquisition of anthracycline resistance in breast tumor cells

Intrinsic or acquired drug resistance is a major impediment to the successful treatment of women with breast cancer using chemotherapy. We have observed that MCF-7 breast tumor cells selected for resistance to doxorubicin or epirubicin (MCF-7(DOX2) and MCF-7(EPI) cells, respectively) exhibited incre...

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Detalles Bibliográficos
Autores principales: Chewchuk, Simon, Guo, Baoqing, Parissenti, Amadeo Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5308870/
https://www.ncbi.nlm.nih.gov/pubmed/28196134
http://dx.doi.org/10.1371/journal.pone.0172244