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Transient inhibition and long-term facilitation of locomotion by phasic optogenetic activation of serotonin neurons

Serotonin (5-HT) is associated with mood and motivation but the function of endogenous 5-HT remains controversial. Here, we studied the impact of phasic optogenetic activation of 5-HT neurons in mice over time scales from seconds to weeks. We found that activating dorsal raphe nucleus (DRN) 5-HT neu...

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Detalles Bibliográficos
Autores principales: Correia, Patrícia A, Lottem, Eran, Banerjee, Dhruba, Machado, Ana S, Carey, Megan R, Mainen, Zachary F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5308893/
https://www.ncbi.nlm.nih.gov/pubmed/28193320
http://dx.doi.org/10.7554/eLife.20975