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Cap-proximal nucleotides via differential eIF4E binding and alternative promoter usage mediate translational response to energy stress

Transcription start-site (TSS) selection and alternative promoter (AP) usage contribute to gene expression complexity but little is known about their impact on translation. Here we performed TSS mapping of the translatome following energy stress. Assessing the contribution of cap-proximal TSS nucleo...

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Detalles Bibliográficos
Autores principales: Tamarkin-Ben-Harush, Ana, Vasseur, Jean-Jacques, Debart, Françoise, Ulitsky, Igor, Dikstein, Rivka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5308895/
https://www.ncbi.nlm.nih.gov/pubmed/28177284
http://dx.doi.org/10.7554/eLife.21907